The Adenosine Receptors Targeted Library is a collection of small molecules specifically designed to target adenosine receptors. Adenosine receptors are a class of G-protein coupled receptors found in various tissues, including the brain, heart, immune cells, and blood vessels. There are four subtypes of adenosine receptors: A1, A2A, A2B, and A3. They are involved in a range of physiological and pathological effects mediated by the binding of adenosine, a signaling molecule, to these receptors.
The purpose of the Adenosine Receptors Targeted Library is to provide researchers with a diverse set of compounds that can selectively interact with adenosine receptors and modulate their activity. By targeting adenosine receptors, researchers can study the role of these receptors in various biological processes and develop potential therapies for diseases and conditions where adenosine receptor modulation is advantageous.
These small molecules can be used for drug discovery and development efforts aimed at designing novel therapeutics that target specific adenosine receptor subtypes. By manipulating the activity of adenosine receptors, researchers can investigate their involvement in diseases such as cancer, inflammation, cardiovascular disorders, and neurologic conditions. Furthermore, the Adenosine Receptors Targeted Library can contribute to the development of more precise and personalized treatments by enabling the selection of compounds that interact with specific adenosine receptor subtypes.
In summary, the Adenosine Receptors Targeted Library is a specialized collection of small molecules designed to interact with adenosine receptors. Its purpose is to facilitate research into the role of adenosine receptors in various biological processes and to aid in the discovery and development of therapeutics targeting these receptors.
Sources:
NCBI: Adenosine Receptors as Therapeutic Targets
NCBI: Adenosine Receptors as Drug Targets – Challenges
PubMed: Focusing on Adenosine Receptors as a Potential Targeted
